Balsamic Chicken with Brussels

Featured in: Midwest Hearty Meals

This vibrant one-pan dish combines juicy chicken thighs glazed with a honey-Dijon balsamic sauce alongside caramelized Brussels sprouts and sweet roasted grapes. The balance of savory herbs and tangy glaze complements the natural sweetness of the grapes, all roasted together for 30 minutes. Ideal for an easy, gluten-free main course, this sheet pan meal requires minimal prep and delivers rich flavors with a crisp-tender vegetable side. Adjust with nuts or alternate cuts for variety and pair with a light red wine to enhance the experience.

Updated on Fri, 13 Feb 2026 15:48:00 GMT
Sheet Pan Balsamic Chicken with Brussels Sprouts and Grapes: golden roasted chicken thighs glazed in tangy balsamic, surrounded by caramelized Brussels sprouts and juicy roasted grapes. Save
Sheet Pan Balsamic Chicken with Brussels Sprouts and Grapes: golden roasted chicken thighs glazed in tangy balsamic, surrounded by caramelized Brussels sprouts and juicy roasted grapes. | epicurestates.com

My friend Sarah showed up to dinner one Wednesday evening with this sheet pan concept, and I watched her toss chicken thighs with Brussels sprouts like she'd discovered some culinary secret. The grapes caught me off guard at first—sweet against savory seemed risky—but when that balsamic glaze hit everything in the oven, the kitchen filled with a smell that made me understand why she kept grinning. One pan, minimal cleanup, and somehow it tasted like you'd spent all afternoon cooking.

I made this for my family last October when the farmers market had just shifted into fall mode, and my brother actually stopped mid-conversation to ask what was in it. That moment when someone's fork pauses and they look up—that's when you know a recipe has staying power. The combination of crispy, caramelized edges on the Brussels sprouts with tender chicken and those sweet pockets of roasted grape made the whole meal feel intentional without any stress.

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Ingredients

  • Boneless, skinless chicken thighs: Thighs stay juicier than breasts during roasting and can handle the heat without drying out—this was a game changer once I stopped automatically reaching for breasts.
  • Olive oil: You're using it twice here, once for the chicken and once for the vegetables, so don't skimp on quality.
  • Dried thyme: Fresh works too, but dried thyme has a deeper, earthier punch that stands up to high heat roasting.
  • Garlic powder: Fresh garlic can scorch at 425°F, which I learned the hard way; powder distributes evenly and stays mellow.
  • Brussels sprouts: Halving them flat-side-down creates those crispy, caramelized edges that make people come back for more.
  • Seedless red grapes: They soften and concentrate into little bursts of sweetness; don't skip this ingredient or you lose the balance.
  • Red onion: The slight sharpness mellows during roasting and keeps everything from feeling too sweet.
  • Balsamic vinegar: The star of the glaze—look for something decent quality that doesn't taste like pure acid.
  • Honey: Balances the vinegar's sharpness and helps the glaze coat everything beautifully.
  • Dijon mustard: Just a tablespoon, but it adds a subtle tang that makes you taste all the other flavors more clearly.

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Instructions

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Set up your oven and pan:
Preheat to 425°F and line your sheet pan with parchment or foil—this saves your sanity on cleanup and prevents sticking. Use a pan big enough that nothing's crowded; you want air to circulate around everything.
Season the chicken:
Toss those thighs with olive oil, thyme, garlic powder, salt, and pepper until they're evenly coated. Don't be shy with seasoning; this is your only chance to flavor the chicken directly.
Dress the vegetables:
In a separate bowl, coat Brussels sprouts, grapes, and onion with olive oil and seasoning until everything glistens. The oil is essential—it's what creates those caramelized, crispy edges you're after.
Arrange on the pan:
Spread the vegetable mixture across the pan first, then nestle the chicken thighs among them. This way the vegetables catch all the chicken drippings and get extra flavor.
Make the glaze:
Whisk balsamic vinegar, honey, and mustard together in a small bowl until smooth. This only takes 30 seconds but transforms everything into something restaurant-quality.
First glaze layer:
Drizzle half the glaze over everything on the pan, coating both chicken and vegetables. You're saving the other half for a finishing touch at the end.
Roast with purpose:
Slide into the oven for 25 to 30 minutes until chicken hits 165°F internally and Brussels sprouts are deeply golden and tender. The time varies slightly depending on chicken size, so don't just trust the clock.
Finish and serve:
Pull it out, drizzle with that reserved glaze while everything's still hot, and serve immediately so you catch all those flavors at their peak. The warmth helps the glaze meld into everything.
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| epicurestates.com

There's something about one-pan meals that changes dinner from a chore into something almost meditative. You prep once, toss everything together, and then you get to sit down while the oven does the heavy lifting—and somehow it still impresses people like you spent hours in the kitchen.

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Why the Grapes Are Actually Genius

I was skeptical about fruit on a savory sheet pan until I tasted them properly caramelized and burst open with heat. The sweetness grounds the balsamic vinegar's tanginess and creates this unexpected complexity that makes people pause and actually taste each bite instead of just eating. It's the kind of move that seems simple once you've done it, but feels revelatory the first time.

Temperature and Timing Matter More Than You'd Think

Chicken thighs are forgiving, which is why I reach for them here, but that 425°F heat is what makes everything else sing. The high temperature caramelizes the Brussels sprouts quickly while keeping the chicken juicy, and the glaze gets slightly sticky and concentrated rather than watery. If your oven runs hot or cool, adjust the temperature slightly or check on things around the 20-minute mark.

Building Flavors Without Fuss

This recipe teaches you something subtle about balancing flavors: the honey softens balsamic's sharp edges, the mustard adds depth without being obvious, and the thyme keeps everything grounded. You're layering umami and sweetness and acid in a way that feels effortless but is actually pretty intentional.

  • Taste your glaze before using it and adjust honey or vinegar if needed based on your preferences.
  • Leftovers reheat beautifully in a 350°F oven for about 10 minutes and taste even better the next day.
  • This pairs perfectly with crusty bread or a simple grain like farro or couscous to catch all the pan juices.
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Savory and sweet Sheet Pan Balsamic Chicken with Brussels Sprouts and Grapes: tender chicken, crispy sprouts, and bursting grapes baked to perfection on a single pan. Save
Savory and sweet Sheet Pan Balsamic Chicken with Brussels Sprouts and Grapes: tender chicken, crispy sprouts, and bursting grapes baked to perfection on a single pan. | epicurestates.com

This sheet pan meal has become my go-to when I want something that tastes like I've been cooking all day but actually respects my time. It's the kind of recipe that quietly becomes part of your regular rotation without you even noticing.

Recipe FAQs

How do I ensure the chicken stays juicy?

Marinating the chicken briefly with olive oil, thyme, and spices before roasting helps retain moisture, and cooking at 425°F ensures it cooks quickly without drying out.

Can I substitute Brussels sprouts with another vegetable?

Yes, you can swap Brussels sprouts for broccoli florets or green beans, but adjust roasting time to achieve tenderness without burning.

What is the role of grapes in this dish?

Roasted grapes add a natural sweetness that balances the tangy balsamic glaze and savory chicken, creating a harmonious flavor profile.

Is it necessary to use Dijon mustard in the glaze?

Dijon mustard adds a subtle sharpness and helps emulsify the glaze, but you can omit it for a milder taste if preferred.

How can this dish be made nutty or crunchy?

Adding chopped pecans or walnuts either before roasting or as a topping adds a pleasant crunch and nutty flavor to complement the tender ingredients.

What wine pairs well with this meal?

A light-bodied red wine like Pinot Noir enhances the sweet and savory notes without overpowering the flavors.

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Balsamic Chicken with Brussels

Tender balsamic-glazed chicken paired with caramelized Brussels sprouts and roasted sweet grapes.

Prep duration
15 min
Cook duration
30 min
Complete duration
45 min


Complexity Easy

Heritage American

Output 4 Portions

Dietary considerations No dairy, No gluten

Components

Chicken

01 4 boneless, skinless chicken thighs, approximately 1 lb
02 1 tablespoon olive oil
03 1 teaspoon dried thyme
04 1 teaspoon garlic powder
05 1/2 teaspoon salt
06 1/4 teaspoon black pepper

Vegetables and Fruit

01 1 lb Brussels sprouts, trimmed and halved
02 1 cup seedless red grapes
03 1 small red onion, cut into wedges
04 1 tablespoon olive oil
05 1/2 teaspoon salt
06 1/4 teaspoon black pepper

Balsamic Glaze

01 1/4 cup balsamic vinegar
02 1 tablespoon honey
03 1 tablespoon Dijon mustard

Directions

Phase 01

Prepare the oven and sheet pan: Preheat oven to 425°F. Line a large sheet pan with parchment paper or aluminum foil.

Phase 02

Season the chicken: In a large bowl, toss chicken thighs with 1 tablespoon olive oil, dried thyme, garlic powder, salt, and black pepper until evenly coated.

Phase 03

Prepare vegetables and fruit: In another bowl, combine Brussels sprouts, red grapes, and red onion wedges with 1 tablespoon olive oil, salt, and pepper. Toss thoroughly to coat all pieces.

Phase 04

Arrange on sheet pan: Spread the Brussels sprouts mixture evenly across the prepared sheet pan. Position seasoned chicken thighs among the vegetables and grapes.

Phase 05

Create the balsamic glaze: In a small bowl, whisk together balsamic vinegar, honey, and Dijon mustard until well combined.

Phase 06

Apply initial glaze: Drizzle half of the balsamic glaze evenly over the chicken and vegetables.

Phase 07

Roast: Roast in the preheated oven for 25 to 30 minutes until the chicken reaches an internal temperature of 165°F and Brussels sprouts are golden and tender.

Phase 08

Finish and serve: Remove from oven and drizzle with remaining balsamic glaze. Serve immediately.

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Necessary tools

  • Large sheet pan
  • Parchment paper or aluminum foil
  • Mixing bowls
  • Whisk
  • Sharp knife and cutting board
  • Instant-read thermometer

Allergy details

Review each component for potential allergens and consult with healthcare professionals if you're uncertain.
  • Contains mustard (Dijon mustard)
  • Review all ingredient labels for potential hidden allergens and cross-contamination risks

Nutritional information (each portion)

These values are offered as a general guide and shouldn't replace professional medical guidance.
  • Energy: 340
  • Fat: 13 g
  • Carbohydrates: 28 g
  • Protein: 28 g

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