Leftover Pizza Grilled Cheese

Featured in: Midwest Hearty Meals

This dish transforms leftover pizza into a warm, crispy delight by folding slices around savory shredded chicken and extra cheese. Buttered and toasted until golden brown, it creates a melty, crunchy meal perfect for a quick snack or satisfying main. Versatile with various pizza styles and simple to prepare, it elevates comfort food using common ingredients and easy technique.

Updated on Fri, 19 Dec 2025 08:16:00 GMT
Golden-brown Leftover Pizza Grilled Cheese with melty cheese and crispy pizza crust. Save
Golden-brown Leftover Pizza Grilled Cheese with melty cheese and crispy pizza crust. | epicurestates.com

My roommate's midnight pizza haul one Thursday became the blueprint for this sandwich when I found myself staring at three cold slices wondering why I was about to eat them plain. The thought struck me: what if I treated leftover pizza like two perfectly good bread slices and filled the gap with something hearty? Twenty minutes later, I was biting into something so unexpectedly good that I made two more before the pan cooled down.

I brought these to a friends house for a casual dinner, and watching someone's face light up when they realized the filling was inside the pizza—not on top of it—made me feel like a culinary genius. Someone asked for the recipe immediately, which might be the best compliment a lazy midnight invention can get.

Ingredients

  • Leftover pizza (2 large slices): Any style works, but a sturdy crust won't fall apart when you fold it; flimsy delivery box pizza will tear, so save the thicker slices.
  • Cooked shredded chicken (1 cup): Rotisserie chicken is your best friend here because it's already seasoned and juicy, but any leftover chicken you have works beautifully.
  • Shredded mozzarella or cheddar cheese (½ cup, optional): This is your ticket to maximum meltiness, though the pizza already has cheese so it's truly optional if you're keeping it simple.
  • Unsalted butter (2 tbsp), softened: Softened butter spreads easier than cold butter and gives you an even golden crust without cold spots.

Instructions

Lay out your canvas:
Take a cold pizza slice and place it cheese side up on your cutting board. The cold pizza is stiff enough to hold its shape, which is exactly what you want right now.
Build the filling:
Scatter about half a cup of that shredded chicken across the cheese side of each slice, then add extra cheese if you're feeling generous. The filling will peek out when you fold, which is part of the charm.
Make the fold:
Fold each slice in half gently, pressing just enough to keep everything tucked inside without squishing the bread. Think of it like closing a book, not squeezing it.
Butter the exterior:
Spread about 1 tablespoon of softened butter on both the outside surfaces of each folded pizza slice. This is what gives you that beautiful golden crust and crispy edges.
Toast the first side:
Heat your skillet over medium heat until a drop of water sizzles gently. Place your buttered folds in, buttered side down, and listen for that satisfying sizzle. Cook for 3–4 minutes until the bottom is deep golden brown and crispy.
Flip and finish:
Carefully flip each one using a spatula, pressing gently as you do. Cook the other side for another 3–4 minutes until the cheese melts and the crust matches the color of the first side.
Rest and serve:
Let everything cool for just a minute so you don't burn the roof of your mouth, then slice each fold in half and serve while it's still hot and the cheese is still stringy.
Cheesy, delicious Leftover Pizza Grilled Cheese with shredded chicken, ready to serve and enjoy. Save
Cheesy, delicious Leftover Pizza Grilled Cheese with shredded chicken, ready to serve and enjoy. | epicurestates.com

My sister tried this for her kids' lunch and texted me a photo of their empty plates, which somehow felt like winning something. It's funny how the simplest hacks sometimes become the ones people actually make again and again.

Why This Works as a Sandwich

The pizza crust has structure and flavor already baked in, so it doesn't need any special treatment to be decent bread. The cheese on the pizza layer acts as a built-in spread, the chicken adds protein and substance, and folding it means everything stays together as you eat instead of falling apart like a regular grilled cheese might. It's like someone already thought through half the sandwich for you, and you're just finishing the job.

Customization That Actually Matters

The magic of using leftover pizza is that you're already committed to whatever toppings are on it. Pepperoni adds a salty kick, veggie pizza gets earthier with the chicken, and if your leftover is already BBQ chicken pizza, you barely need to think. Don't overthink the additions—the pizza base is doing most of the heavy lifting.

  • A drizzle of hot sauce on the inside before cooking kicks everything up a notch without making a mess.
  • Fresh herbs like basil or oregano scattered on the filling layer will release their aroma into the whole sandwich.
  • Marinara or ranch for dipping on the side turns this into something even your pickiest friends will finish.

The Right Equipment Matters More Than You'd Think

A nonstick skillet is honestly worth it here because you can use less butter and watch everything cook without obsessing over sticking. The spatula should be flexible enough to get under the fold smoothly but sturdy enough that it doesn't bend under the weight. I learned this the hard way when my flimsy old spatula folded in half mid-flip and I had to start over.

Mouthwatering image: a close-up of a perfectly toasted Leftover Pizza Grilled Cheese sandwich. Save
Mouthwatering image: a close-up of a perfectly toasted Leftover Pizza Grilled Cheese sandwich. | epicurestates.com

This sandwich is proof that some of the best meals come from asking what if when you're staring at leftovers. Give it a shot and let it become your own thing.

Recipe FAQs

Can I use any type of pizza for this dish?

Yes, any leftover pizza with a sturdy crust works best, including pepperoni, veggie, or BBQ chicken styles.

Is additional cheese necessary when adding shredded chicken?

Extra shredded mozzarella or cheddar is optional but helps create a richer, meltier filling.

What type of pan is recommended for toasting?

A large nonstick skillet ensures even heating and easy flipping for a golden, crispy finish.

How long should the folded pizza cook on each side?

Cook for 3–4 minutes per side over medium heat until the crust is golden and cheese has melted.

Can I add toppings or sauces inside before toasting?

Absolutely, adding herbs, hot sauce, or dippings like marinara or ranch can enhance flavor profiles.

Leftover Pizza Grilled Cheese

Crispy folded pizza loaded with juicy shredded chicken and melted cheese in minutes.

Prep duration
5 min
Cook duration
8 min
Complete duration
13 min


Complexity Easy

Heritage American

Output 2 Portions

Dietary considerations None specified

Components

Main

01 2 large slices leftover pizza (any style with sturdy crust)
02 1 cup cooked shredded chicken (rotisserie or leftover)
03 ½ cup shredded mozzarella or cheddar cheese (optional)

For Toasting

01 2 tablespoons unsalted butter, softened

Directions

Phase 01

Prepare Pizza Base: Place a cold pizza slice on a cutting board, cheese side facing up.

Phase 02

Add Chicken and Cheese: Spread half a cup of shredded chicken evenly over the cheese side of each pizza slice; sprinkle extra cheese if desired.

Phase 03

Fold Pizza Slices: Fold each pizza slice in half, pressing gently to enclose the filling securely.

Phase 04

Heat Skillet and Butter: Heat a large nonstick skillet over medium heat and spread one tablespoon of butter on the outside of each folded pizza.

Phase 05

Toast First Side: Place folded pizzas buttered side down in the skillet; cook for 3 to 4 minutes until golden brown and crisp.

Phase 06

Toast Second Side: Flip each folded pizza, press gently with a spatula, and cook for another 3 to 4 minutes until cheese melts and crust is golden.

Phase 07

Serve: Remove from heat, let rest for one minute, slice in half, and serve warm.

Necessary tools

  • Large nonstick skillet
  • Spatula
  • Knife and cutting board

Allergy details

Review each component for potential allergens and consult with healthcare professionals if you're uncertain.
  • Contains wheat (pizza crust), milk (cheese and butter), and possible egg (pizza base or toppings)
  • Contains chicken (meat)
  • Check for additional allergens such as soy or nuts depending on pizza and chicken used

Nutritional information (each portion)

These values are offered as a general guide and shouldn't replace professional medical guidance.
  • Energy: 480
  • Fat: 23 g
  • Carbohydrates: 38 g
  • Protein: 32 g